Yes, you can setup different rates for a Channel and/or you can use a Price Multiplier to change your Rates/Daily Price for a Channel. The price can be increased/decreased. Check the HELP page for the Channel for more information.
=== Can I send different inventory/availability to different channels? ===
Yes, once you have setup the connection to a channel, then you can manage the inventory in Settings > Channel Manager > Channel Inventory.
You will see a row for each channel set the inventory for each channel/date.
== Currencies ==